Death receptor 3 (DR3) gene duplication in a chromosome region 1p36.3: gene duplication is more prevalent in rheumatoid arthritis

Gene Duplication in Insecticide Resistance

Gene duplication is a widely observed phenomenon in all three kingdoms of life and is considered to be a major driving force in the evolution of genomes and organisms. Gene duplication refers to any duplication event of a region of DNA that contains genes, eventually giving rise to gene families. In a classical sense, gene duplication is considered to predate functional diversification. When a ...

GENE DUPLICATION IN SACCHAROMYCES CEREVZSZAEl

Five independent duplications of the acid-phosphatase (aphtase) structural gene (acpl) were recovered from chemostat populations of S. cerevisiae that were subject to selection for in vivo hyper-aphtase activity. Two of the duplications arose spontaneously. Three of them were induced by UV. All five of the duplication events involved the transpositioning of the aphtase structural gene, acpl, an...

Gene duplication and evolution.

Lynch and Conery (1) presented one of the first serious efforts to study the evolutionary fate of gene duplication using genomic sequence data. Their analysis led to several interesting observations, particularly with respect to the rate of gene duplication in eukaryotic genomes and the subsequent halflife of duplicates. These two parameters are of particular importance in studying the evolutio...

Gene and genome duplication.

Genomic sequencing projects have revealed the productivity of processes duplicating genes or entire chromosome segments. Substantial proportions of the yeast, Arabidopsis and human gene complements are made up of duplicates. This has prompted much interest in the processes of duplication, functional divergence and loss of genes, has renewed the debate on whether an early vertebrate genome was t...

Gene duplication in bacteria: alteration of gene dosage by sister-chromosome exchanges.